High Content Screening Analysis

High content analysis hca or high content screening hcs combines high throughput automated imaging and analysis to extract quantitative multi parametric data at the single cell level.

High content screening analysis.

Assessing a vast number of compounds is time consuming therefore acquiring a large number of high resolution cellular images with fast scanning speed is critically important for drug screening. The hypercyt high throughput ht flow cytometry sampling platform uses a peristaltic pump in combination with an autosampler and a novel approach to data collection to circumvent time delay bottlenecks of conventional flow cytometry. High content screening hcs also known as high content analysis hca or cellomics is a method that is used in biological research and drug discovery to identify substances such as small molecules peptides or rnai that alter the phenotype of a cell in a desired manner. This approach also dramatically reduces the amount of sample aspirated for each analysis typically requiring 2 μl per sample while making.

Hence high content screening is a type of phenotypic screen conducted in cells involving the analysis of whole cells or. The hcs team has expertise in all areas of high content image based screens including sample preparation image acquisition image analysis image data management and algorithm development. For assay development and screening of non imaging assays refer to assay development and high throughput screening. High content analysis hca high content analysis is a principle methodology for so called phenotypic screening in drug discovery and development process.