High Content Screening System

However one of the main problems arising from this approach is spectral crosstalk which can limit assay sensitivity.

High content screening system.

They feature options and modules to address your specific research including objectives filters imaging modes and. Designed for researchers looking to increase their screening throughput the platform offers common excitation wavelengths for fluorescence and white light illumination for colorimetric samples. The opera phenix plus high content screening system is the premier confocal solution for today s most demanding high content applications. High content screening hcs in cell based systems uses living cells as tools in biological research to elucidate the workings of normal and diseased cells.

Perkin elmer the opera phenix plus high content screening system is designed for fast response analysis of physiologically relevant model systems which adds fast frame rate image capture for. High content screening hcs systems can be used for high throughput screening of drugs in human embryonic stem cells hescs. Our high content confocal imaging systems based on the csu are the ideal solution for drug screening using elaborated 3d and live cell assay systems as well as 2d fixed samples. However hescs require immunofluorescence staining with stemness markers e g oct 4 prior to hcs which can be time consuming and labor intensive in this study we employed transgenic hescs with enhanced green fluorescent protein driven by stemness gene oct 4.

With the compact and powerful cellinsight cx5 high content screening platform you can read and analyze a 96 well plate in under four minutes. Drawing on over a decade of experience with the industry leading opera and opera phenix system the opera phenix plus is designed for high throughput high content assays phenotypic screening assays using complex disease models such as live cells. High content screening hcs is a well established approach for the multiparametric analysis of cellular events. High content screening is a combination of modern cell biology with all its molecular tools with automated high resolution microscopy and robotic handling.

Hcs is also used to discover and optimize new drug candidates. User friendly high content analysis software cellpathfinder with its versitile functionalities powerfully supports the analysis of various phnotype changes and target. Since its first introduction more than a decade ago high content imaging systems have continually evolved with many improvements enabled to meet user demands of greater flexibility and the growing requirements of assays involving complex cellular disease models. Simultaneous multi color imaging is a technology commonly used to increase the speed of high content screening systems.

An end to end solution for high content imaging and analysis.